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Participants taking bofanglutide experienced weight loss and improvements in various cardiometabolic risk factors

This helps in understanding the downstream effects on cellular proliferation, differentiation, and metabolism

Before taking GLP-1s, there also needs to be in-depth conversations about what you're signing up for, the risks and benefits, and the long-term plan for treatment

Tirzepatide (sold as Zepbound for weight loss, Mounjaro for diabetes) produces the most weight loss of any approved drug: about 22.5%

While Ozempic only has approval for treating type 2 diabetes, doctors can also sometimes prescribe it off-label for weight loss

Subgroup analysis revealed a marginal elevation of ROR for suicide and self-injury with GLP-1RA in children, but no safety signal was detected by EBGM05 in this population