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Despite oral B12 supplementation, her levels remain low

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Mechanistically, 1,25(OH)D facilitates the formation of VDRRXR heterodimers, which are recruited to antioxidant response elements (AREs), inducing Nrf2 and its downstream targetsincluding HO-1, NQO1, and SOD2and thereby enhancing ROS scavenging capacity [190, 191]

Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks