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GSH is synthesized in two steps from the constituting amino acids, but in this synthesis a transport step is of utmost importance
The BBB drastically limits native peptides
Abstract Aim The aim of this study was to evaluate oxidative stress from glutathione depletion in critically ill patients with a septic shock through the abnormal presence of pyroglutamic acid (PyroGlu) in the urine (indirectly) and through its serum level (directly)
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