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It has been studied specifically for its role in intestinal inflammation, with preclinical research showing it can reduce pro-inflammatory cytokine activity in gut tissue

A hemisected colonic tissue preparation (Mao et al., Figure 3E), was used to compare calcium responses evoked by neuronal exposure to Ex-4 before and after mucosal application of indole

Musicki, B., Liu, T., Lagoda, G

X-linked or partial defects can be unmasked by stress (e.g., sepsis, critical illness, steroids, fasting, surgery, pregnancy)

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