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Occasionally, the lesions may be traumatized and irritated by clothing or accidentally scratched and ulcerated

doi: 10.1007/s00774-011-0321-5

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And along with the extra blood is something that can be kind of scary to see: clots

The transformation of inosine to hypoxanthine is catalyzed by purine nucleoside phosphorylase, and eventually hypoxanthine utilizes the dual oxidation of xanthine oxidase (XO) to produce uric acid

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