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The combination is potent because it addresses psoriasis at both the regulatory level, why the immune system is attacking, and the effector level, the specific inflammatory signals doing the damage

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Together, they form the basis of what many researchers call the 'Wolverine' protocol, a nod to the comic book character's famous healing factor

Preclinical in vivo models have examined its effects on nitric oxide synthase activity, extracellular matrix protein expression, and actin cytoskeletal dynamics in connective tissue contexts