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Nausea is the most frequent side effect, appearing in 2540% of users within three to seven days of starting treatment

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Apovian wasnt affiliated with the study

For instance, DDX5 (p68) has been demonstrated to act as transcriptional co-activator of Polo-like kinase-1 (PLK1) by stimulating the transcription from PLK1 responsive promoter

This phenotype is consistent with the concept that smaller cells are primarily engaged in proliferation, whereas larger cells often shift to alternative metabolic activities, diverting energy from replication to other cellular processes (Vander Heiden et al., 2009)