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You can expect redness and point bleeding at the injection sites, numbness in the actual injected area that will last a few hours, and very mild swelling (often described as tightness or firmness) that you feel but others would not likely notice

The best established application of this IGF 1 peptide is industrial rather than physiological: LONG R3 IGF-I is a standard growth factor supplement in serum-free CHO and HEK293 culture, where Morris and Schmid (Biotechnology Progress, 2000) compared it directly against insulin

A standard U-100 insulin syringe has markings from 0 to 100 units

J Med Sci Clin Res

Any changes are usually subtle and gradual, noticed over several weeks rather than days

Most patients notice initial improvements in 2-4 weeks, meaningful firmness and fine line changes at 4-8 weeks, and peak early results at 8-12 weeks