This guide covers every major GLP-1 drug pipeline candidate worth watching in 2026: the compounds already approved, the assets awaiting regulatory decisions, and the emerging molecules that could define the next decade of metabolic medicine
Time Window (Start and End Dates): The search included studies published from the database inception to July 2025
blood pressure may decrease alongside weight loss, and any cardiovascular effects should be interpreted in the context of overall trial data rather than assumed to be adverse
Ozempic is FDA-approved for type 2 diabetes
Since appetite may decrease, patients need to make every meal count
If TSH, free T4, or heart rate changes significantly, reporting this to your care team allows dose adjustment or therapy modification