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It is extracted from Chinotto a fruit-bearing tree native to Southern China (hence its name) which was imported in Italy most probably around the VI and VII century A

Consequently, riboflavin may significantly enhance cell longevity by boosting the activity and concentration of antioxidant enzymes, such as superoxide dismutase, catalase, and glutathione peroxidase, that act on deactivating peroxides, which may create an oxidant environment (43)

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Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of a non-catalytic ligandin site

Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis