Tirzepatide activates both GLP-1 and GIP receptors, while semaglutide activates GLP-1 only
Wegovy (semaglutide) is an effective injectable medication that helps people with a BMI of 30 or over lose weight
For context, retatrutide vs semaglutide data shows retatrutide producing roughly 50% more weight loss than the highest approved semaglutide dose
Mouse studies dosed 25 mg/kg IP twice daily not directly translatable to humans
Based on the drug class, the global GLP-1 receptor agonist market is segmented into semaglutide, dulaglutide, liraglutide, exenatide
Competing Interests Professor Melanie Davies has acted as a consultant/advisor and speaker for Eli Lilly, Novo Nordisk and Sanofi, has attended advisory boards for Abbvie, Amgen, AstraZeneca, Biomea Fusion, Carmot/Roche, Sanofi, Zealand Pharma Regeneron, GSK and EktaH and as a speaker for AstraZeneca and Boehringer Ingelheim