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IGF1 indirectly increases DNA repair by 50% through increasing the p53 dependence in the p21, while inhibition IGF1R by siRNA in human prostate cancer cells enhances the sensitivity of ionizing radiation to SSBs and DSBs (Clark et al., 2005)

Previous research has demonstrated that ILF3 functions as a crucial transcription factor in regulating the transcription and expression of downstream molecules [38, 39]

l-carnitine deficiency develops over time in haemodialysis patients and serum levels may not differ from controls in incident patients [15]

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However, referrals to specialists and waiting list times have a particular relevance in view of the number of symptoms and co-existing illnesses PA sufferers may have