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Women using oral contraceptives should use a non-oral contraceptive method or add a barrier method for 4 weeks after starting tirzepatide and after each dose increase to maintain contraceptive effectiveness

A 3-armed forced choice (3-AFC) method can be applied to monitor the subject's response for detection and reorganization of taste (Mossman and Henkin, 1978)

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No, creatine supplementation is not recommended in patients with reduced renal function, and this patient has kidney impairment