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Ethics declarations Ethics approval and reporting guidelines This retrospective cohort study protocol was approved by the Mass General Brigham Institutional Review Board
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Once significant weight loss is achieved, some individuals may continue the medication at a lower maintenance dose, while others may transition to other weight management strategies
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Retatrutide is a stronger incretin backbone than semaglutide, which makes the prediction less obvious additive effects often shrink as the base compound's efficacy rises
It can also affect hormone levels, kidney function, and glucose metabolism
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