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In a GSH-dependent manner, PRDX6 functions as a selenium acceptor and carrier, transferring selenium to selenophosphate synthetase 2 (SEPHS2) to support selenocysteine-tRNA synthesis required for GPX4 translation 106

Peng W., Liu F., Zhang L., Zhang L., and Li J., Design, Synthesis, and Evaluation of Tricyclic Compounds Containing PhenylTetrazole as XOR Inhibitors, European Journal of Medicinal Chemistry 246 (2023): 114947, 10.1016/j.ejmech.2022.114947

The spectrum of NAFLD ranges from nonalcoholic fatty liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma [3]

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