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[48] Holmes-Hampton GP, et al

Again, these higher expression levels observed in APP/PS1 animals suggests a genotype-related transcriptional regulation, which may be related to increased hippocampal oxidative stress in transgenic animals (Aso et al., Whether this regulated Gpx4 mRNA variant constitutes an intermediate processing stage of Gpx4 splicing or represents a different level of transcriptional regulation by intron retention remains unrevealed

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These concerns can deter them from continuing treatment