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Follow-up studies combining mitochondrial metabolite profiling, organelle transport assay and structure-guided mutagenesis identified a critical role of SLC25A39 in mitochondrial glutathione uptake, a discovery that has also been independently reached by a recent report 14

Using a GSH synthesis inhibitor, DL-Buthionine-[S,R]-sulfoximine (BSO), the spontaneous proliferation induced by HTLV-1 was impaired in peripheral blood mononuclear cells (PBMC) from infected donors

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