The underlying mechanisms could involve the reduction of serum IL-1 and neutrophils by activating the Nalp3 inflammasome
Pande AH, Sandeep, Anakha J (2026)
Evidence has suggested a quercetin-rich fruit, guava, is able to protect against type 2 diabetes mellitus-induced renal and pancreatic dysfunction by preventing cell apoptosis, autophagy, and pyroptosis (Lin et al., 2016)
Cancer Genet Cytogenet 1999
This improves cellular uptake and results in higher intracellular delivery than conventional glutathione forms
Liensinine (LIEN), as an isoquinoline alkaloid, activates the TAK1/AMPK pathway to reduce PA-induced lipid accumulation and ROS generation in hepatocyte models in vitro , while bidirectionally regulating lipid metabolism-related proteins in HFD-induced mice - downregulating FAS, SCD, and PPAR while upregulating PPAR , UCP2, and CPT-1 (Zhang W