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GHK-Cu promotes angiogenesis (new blood vessel formation), which raises theoretical concerns about supporting tumor growth, though the peptide also demonstrates documented anti-cancer gene expression effects

Above certain plasma concentrations, arginase activity increases to compensate, further limiting how much arginine stays available for NOS

Contraindications: Do not use in the same routine as direct Acids, EUK 134 0.1%, retinoids, pure or ethylated vitamin C, or peptides

Stress-management techniques like journaling or deep breathing also help regulate appetite-related hormones

The copper coordination geometry matters for activity

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