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Description

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Kozakova M, Morizzo C, Goncalves I, Natali A, Nilsson J, Palombo C

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ReACp53, designed by Soragni et al., is a peptide that suppresses mutant p53 aggregation, restores the wild-type conformation of mutant p53, and promotes its nuclear localization to increase its transcriptional activity

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However, a TIGAR inhibitor can inhibit stearoyl-CoA desaturase 1 (SCD1), which induces ROS and promotes ferroptosis [105, 108]

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