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The first psoriasis study was called TOGETHER-PsO , and the psoriatic arthritis study was called TOGETHER-PsA

It names a history of acute kidney injury, severe dehydration, pancreatitis, or cognitive concerns as reasons to avoid the combination or pursue it only under intensive monitoring

Pharmacokinetic/pharmacodynamic studies in drug product development

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doi: 10.3389/fendo.2021.582519 80