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In Parkinsons disease models, riboflavin activates the Nrf2/HO-1 pathway, mitigating mitochondrial complex I-mediated ROS overproduction and safeguarding dopaminergic neurons (e.g., substantia nigra) (64)

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This translates to a trailing price-to-earnings (P/E) ratio of 18.6x, significantly below the 5-year mean of 35x and 10-year mean of 29x

Collectively, our findings establish the 1,2-dithiolane architecture as a dual-mode molecular scaffoldthrough strategic incorporation of hydroxyl or amino moieties as cargoesthat achieves orthogonal responsiveness to distinct redox regulators (e.g., thiols vs