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Theres no single universal definition of what constitutes a microdose of semaglutide or a microdose of tirzepatide

The medical goal is bigger than a number

Body weight and BMI play a role in determining eligibility for weight management trials, with most retatrutide studies enrolling adults with a BMI of 30 kg/m or above, or 27 kg/m or above in the presence of weight-related comorbidities such as hypertension or dyslipidaemia

Trina Wilcox: So, who should and should not consider trying these medications

Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously a mechanism that sets it apart from existing agents such as semaglutide and tirzepatide

Importantly, weight loss itself provides no benefits to pregnant patients and may cause fetal harm