The SLC25 carrier family: important transport proteins in mitochondrial physiology and pathology
Nicotinomide (vitamin B3) has been shown to be liver toxic in doses over 3G per day
Istivan TS, Pirogova E, Gan E, Almansour NM, Coloe PJ, Cosic I
demonstrated the topiramate linearity of the pharmacokinetics in plasma, while its clearance from whole blood seemed to increase with escalating doses (Shank et al., 2005)
Max-Planck-Institut fr Biochemie, Abt
Lycium barbarum polysaccharide counteracts this hepatotoxicity by preserving mitochondrial integrity and activating Nrf2 signaling, supporting its potential as a protective agent against cadmium-induced liver damage (126)