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In addition, the treatment with NP4 reduced the level of anti-inflammatory M2-type macrophages by 20% in comparison to the treatment with NP2 (Supplementary Fig

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Study findings The study cohort consisted of 36,082 and 234,028 GLP-1 receptor agonist and DPP-4 inhibitor users, respectively, who were followed for a median of 1.3 and 1.7 years