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When used together, their opposing actions require careful monitoring and provider coordination to maintain therapeutic efficacy

While GLP-1 medications can be highly effective for sustainable weight loss , maintaining results after stopping treatment often depends on the habits, metabolic health, and support systems built during the process

However, always inform your prescriber about all medications you are taking, including semaglutide

Eating protein first during meals, including healthy fats, and consuming plenty of fiber can naturally boost GLP-1 production in your body

The team found that, compared to the placebo, 22% fewer people experienced kidney-related events in the group of 8,803 people who received a once-weekly injection of semagutide (2.4 mg)

Internist (Berl) 21(7):371-5, 1980