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PMID: 40935835 Cheng J et al

doi: 10.1016/j.jpba.2016.08.020 11

Rapid Commun Mass Spectrom 35(10):e9074

Microsomes (1 mg/ml) in sodium phosphate buffer, pH 7.4 were supplemented with NADPH (10 mM) and NFT (5 mM)

Notably, metabolites involved in PPP, purine and pyrimidine metabolism were slightly decreased, whereas TCA cycle intermediates increased in HeLa cells expressing Cr GPDH compared to luciferase (LUC) control ( Figure 3e-h )

Further effectors are the Interferon-induced myxoma resistance protein 1 (MX1) and the Polymeric immunoglobulin receptor (PIGR), which represented 0.05 and 0.1% of the total proteome abundance and were 1.8 and 1.5-fold induced, respectively