Many individuals who find it difficult to lose weight despite a caloric deficit may be dealing with this cortisol trap. They often experience fatigue, brain fog, and intense cravings for high-calorie comfort foods, as the body seeks a quick energy source to cope with the perceived stress
What we can do (in some but not all cases) is to lighten the shade of your lips by 1-2 shades lighter, acknowledging that over time & sun exposure, you WILL regress back to your constitutional (genetically predetermined pigment)
Penzo-Mendez AI (2010)
It has strong recognition in the sports nutrition market
It also cannot answer bigger diabetes questions on its own, such as why HbA1c changed, whether your current regimen is adequate, or whether weight loss, meal planning, or medication timing is driving most of the problem
In the meta-analysis of 3 studies 20,28,32 which compared a GLP-1-based therapy against a comparator, GLP-1-based therapies were found to increase % FMD non-significantly (mean difference [95% CI] in the changes from baseline: 1.65 [0.89, 4.18] %