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GHK-Cu focuses on copper-mediated collagen synthesis and antioxidant activity valuable for skin and wound research, but absent the vascular and neuroprotective dimensions of the compounds profile

Although LDHA has been extensively characterized as a tumor survival factor through its role in mitigating ROS, targeted depletion via small interfering RNA or pharmacological inhibition (GSK2837808A or R-GNE-140) fails to sensitize A549 cells to ferroptosis inducers, including RSL3 or erastin (49)

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A pilot study in young adults found that lion mane supplementation improved processing speed, and researchers attributed this partly to BDNF-like neurotrophic effects