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Results Here, we report the first orally administered, pH-responsive liposomal formulation of the HS donor GYY4137, specifically designed for colon-targeted delivery

10.1021/acs.jproteome.6b00733 11 DAlessandroA.XiaY

However, the liposome construction module of CHARMM-GUI does not contain PEGylated lipids, therefore the initial model of Doxil, Onivyde and Exparel was constructed using the liposome construction module in FormulationMM

Here are steps- Exclude internal or endocrine causes of skin darkening

10.1371/journal.pone.0247307 39