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Iron ions are essential for cell metabolism and survival, but excess free iron ions lead to increased intracellular oxidative stress, which promotes cell death, especially ferroptosis [42, 43]

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Nevertheless, orange urine can also be caused by over consumption of carrots or vitamin B2, while some forms of medication can also lead to orange urine, including sulfasalazine, phenazopyridines, isoniazid and some types of laxative medication

10.1016/j.niox.2011.04.004 70 CrabtreeM

However, without a preservative, these must be used all at once