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Other combinations of entero-pancreatic hormones, including cagrisema (GLP-1/amylin RA) and the triple agonist retatrutide (GLP-1/GIP/glucagon RA), have progressed to phase 3 trials as obesity treatments, and early data suggest that they may lead to even greater weight loss than tirzepatide [28]

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Differential response of the natriuretic peptide system to weight loss and exercise in overweight or obese patients

Patients eat less, feel fuller for longer and burn more energy, which may explain the promising results seen in trials

When combined, these ingredients work together to support a healthy immune system and optimal digestive function

doi:10.3748/wjg.v31.i37.111435