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The researchers were particularly interested in whether ARA-290 could reduce the reaction of the neurons to capsaicin
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The lead postbiotics, AL0044 (garlic extract-derived) and AL0047 (senna leaf-derived), achieved TMA lyase inhibition comparable to that of the synthetic reference inhibitor FMC
In addition, the conversion process creates small amounts of cyanide as a toxic byproduct
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Cells were incubated with QIs or parent compounds for 2.5 h, based on the time-dependency of QIs-induced loss of cell viability (Supplementary Figure S3)
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