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Until we have larger, more definitive studies, the safest approach is still to stop GLP-1 medications before trying to conceive. The findings, however, are exactly the kind of data we need to justify properly designed prospective trials, says Lora Shahine, MD, a reproductive endocrinologist and obstetrician-gynecologist at PNWF IVY Fertility Center in Bellevue, Washington, and host of the Brave and Curious podcast

Pregnancy, breastfeeding, major illness, surgery, eating disorders, gastroparesis, and major weight changes can all affect insulin planning

(New England Journal of Medicine) More recent work continues to explore body composition and muscle function alongside GLP-1 therapy

How do I calculate the dose in syringe units

But how long does it remain safe to use

The timeline is pretty predictable: you might feel slightly tired for the first couple hours as your body processes everything, then experience an energy boost that coincides with that coveted glow