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*PLoS ONE*, 8(12), e79913

What results to expect and when Setting realistic expectations prevents frustration and premature protocol abandonment

It is best to avoid or strictly limit alcohol while taking pyridostigmine

Excessive NAM depletion directly reduces the substrate supply for NAD+ synthesis, leading to decreased intracellular NAD+ levels

Introducing a second agent with a different mechanism can restart progress by circumventing the specific adaptations the body made in response to the first compound