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However, semaglutide significantly reversed these changes, indirectly reducing the visceral adipocyte content in adipose tissue

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These agents vary in receptor affinity, duration of action, molecular size, and ability to cross biological barriers, which likely translates to different efficacy profiles in the eye

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The lipolytic stimulus is characterized by the reduction of fat cells through inhibition of the adenosine or phosphodiesterase receptor, activation of the beta adrenergic receptor or inhibition of the alpha 2 receptor