On December 22, 2025, the FDA approved Novo Nordisk's once-daily oral semaglutide (Wegovy pill, 25 mg) for chronic weight management and cardiovascular risk reduction (FDA / Novo Nordisk, 2025)
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While adult obesity rates have driven commercial focus, childhood obesity has reached epidemic proportions globally, with limited therapeutic options available for younger patients
Notably, a 24-week semaglutide trial reported improvements in sperm morphology and cholesterol levels while maintaining stable hormone levels
People who train consistently, eat enough protein, and manage their deficit intelligently throughout their time on the drug retain the majority of their lean mass and face none of the downstream consequences associated with significant muscle loss