The following criteria were considered: Full economic evaluations: cost-utility analysis, cost-effectiveness analysis, cost-benefit analysis Economic evaluations reporting incremental cost-effectiveness ratios (i.e., cost per quality-adjusted life year/life years gained or cost per event avoided) Studies in patients with confirmed vitamin B12 deficiency Studies in English Abstracts were reviewed by a single reviewer and, for those studies meeting the eligibility criteria, full-text articles were obtained
Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)
[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Choueiri TK, Pal SK, McDermott DF, Morrissey S, Ferguson KC, Holland J, et al
Boyle, K
Heres how vitiligo impacts a persons physical and psychological health Vitiligo is an auto-immune condition that causes skin de-pigmentation resulting in the formation of white patches on ones skin
Hypertension at baseline was determined based on the principal investigators discretion