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GPx3 has been reported to inhibit the proliferation and metastasis of lung and liver cancer cells via inhibition of the extracellular signal-regulated kinase (ERK)/nuclear factor-B (NF-B) pathway (An et al

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During this process, glutathione transforms into glutathione disulfide, or oxidized glutathione (GSSG), and is regeneratedwith the help of an energy source like glucoseby the enzyme glutathione reductase (GR)

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