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Polyphenols in health and disease: gut microbiota, bioaccessibility, and bioavailability

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Concurrent with diet and microbiota composition, TMAO plasma levels also reflect age 17 , sex 18 , kidney function 19,20,21 , and chronic diseases 7,22

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To bridge the gap between preclinical findings and clinical application, future research on forskolin and carotenoids should prioritize human safety and tolerability to establish optimal dosing and formulation