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In findings from a phase 2a trial that were presented at the American Diabetes Association Scientific Sessions and simultaneously published in The Lancet , 71% of adults receiving coadministered cagrilintide and semaglutide 2.4 mg, dubbed CagriSema (Novo Nordisk), lost at least 10% of their body weight, and 89% of adults achieved an HbA1c of less than 7% with the combination therapy

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10.1126/science.adl0495 Science 27 ChangC.AdiP.MulyaniR.LinC.ListyaningrumR.SantosoS.et al (2025)

Subjects might exhibit increased stamina and a general uptick in perceived energy levels