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Tissue volume fractions determined from the segmented images were used to correct metabolite concentrations for partial volume effects and relaxation attenuation in each voxel [53]

Given its role in shaping the tumor immune microenvironment and promoting inflammasome activation, TXNIP-targeted modulation may enhance responses to immune checkpoint inhibitors such as PD-1/PD-L1 blockade

Additionally, the efficacy of epigenetic drugs has been limited primarily to hematological malignancies, proving largely ineffective in solid tumors, possibly due to metabolic and epigenetic heterogeneity within tumors

electrocardiograms were also performed at these time points

Retrieved from: Rebouche, C

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