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PSEN1 and PSEN2
The growing preclinical and early clinical evidence supports their potential as a transformative therapy in this population
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In metabolomics, significant alterations were observed in metabolism related to arginine and proline, arachidonic acid, glutathione metabolism, and ubiquinone and other terpenoid-quinone biosynthesis pathways as CKD progressed with further metabolomic analyses revealing that variations in the distributions of pro-oxidant and toxic metabolites from the four identified metabolic pathways were observed in the feces and serum of the patients as the disease progressed
Beta-arrestin2 and c-Src regulate the constitutive activity and recycling of mu opioid receptors in dorsal root ganglion neurons
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