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Early data shows impressive weight loss (15-20% body weight), but durability wanes off-drug

You can work with your doctors to screen for qualifying conditions, says Dr

The most common side effects are mild nausea, bloating, or digestive changes, especially in the first few weeks

Bikman emphasized that eating patterns, like frequent snacking , can reduce insulin sensitivity, contributing to age-related metabolic decline

The evolving framework under ICH S1B(R1) further emphasizes a modern, evidence-integrated approach to long-term safety evaluation