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Recently, the introduction of highly effective glucagon-like peptide-1 (GLP-1) receptor agonists has led to increased utilization of obesity medications in this population

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Tesamorelin protocol: Subcutaneous injection, 5 days on / 2 days off Inject fasted (at least 13 hours after eating) Dosing in the morning (before breakfast) is also an option, but without eating for 30-60 minutes after dose Reconstituted from lyophilized powder with bacteriostatic water Rotate injection sites to prevent irritation Sermorelin protocol: Subcutaneous injection, daily Best administered before bed to align with natural nocturnal GH release Inject fasted (at least 13 hours after eating) Dosing in the morning (before breakfast) is also an option, but without eating for 30-60 minutes after dose Reconstituted from lyophilized powder with bacteriostatic water Upper outer thigh is the preferred injection site What to expect timeline-wise (both peptides): Weeks 14 : Improved sleep quality is often the first noticeable change

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