Here, it creates a strong osmotic effect, drawing water into the gut and frequently resulting in painful cramping, bloating, and osmotic diarrheaa phenomenon commonly referred to as reaching "bowel tolerance." For patients with MCAS or Long COVID who already suffer from severe gastrointestinal dysmotility, these side effects can make standard high-dose Vitamin C intolerable
That being said, he stresses that the primary objective of the episode is not to solely focus on identifying a specific supplement or combination of supplements capable of transforming ones overall health
doi: 10.1146/annurev.arplant.47.1.127
They also use a specific product under controlled conditions
Other differences include half-life (tirzepatide ~5 days, semaglutide ~7 days), dosing ranges, and available formulations
Inverse association between carotid intima-media thickness and the antioxidant lycopene in atherosclerosis