Financial issues, layoffs, business progress, and financing can often lead to unforeseen consequences
Fully adjusted model: Adjusted for demographic factors, comorbidities and medication
Two estimands were employed: the trial product estimand, which evaluated treatment effects assuming perfect adherence to the assigned regimen, and the treatment policy estimand, which included all randomized participants regardless of adherence
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Understanding how they workand where they may fall shortcan help patients make more confident health decisions