[36], they showed the ability to proliferate after re-exposure to peak protein by rapidly increasing ICOS and CD40L levels in CXCR5 + and CXCR5, as well as the expression of Th1- and Th17-associated cytokines
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It is also not recommended for patients with existing gastrointestinal disease to avoid potential side effects or exacerbating the condition.107 Further, serious risks associated with Tanzeum use include pancreatitis, acute kidney injury, renal impairment, and pneumonia, further limiting its use in specific conditions or susceptible patients
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