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The pivotal Phase 2 trial (NCT04881760), published in The New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with BMI 30 or higher

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The triple-agonist mechanism that makes retatrutide so effective at burning fat may actually offer a metabolic advantage when it comes to preserving lean tissue

19 Glucagon-like peptide-1 receptor agonists Many of the large-scale CV outcome trials of glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes have included kidney disease outcomes as secondary outcomes

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And what will the ripple effects be for patients as the health economy rebalances itself around novel paradigms for which long-term evidence is still being generated