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The studies, which provide new results from two clinical trials, compared the effects of semaglutide versus placebo in reducing heart failure-related symptoms, physical limitations, weight and heart failure hospitalizations in patients with obesity and heart failure with preserved ejection fraction, or HFpEF

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For example, studies on liraglutide and semaglutide have shown substantial reductions in body weight in both diabetic and non-diabetic populations [42,43]

Review in-vitro/in-vivo study results